6,829 research outputs found

    Of, By, and For the Community: The Story of PUENTE Learning Center

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    Reviews the 20-year development of the learning centers, located in East and South Los Angeles. Examines the impact of the center's preschool, kindergarten, and after-school programs for youth, and education and job training programs for adults

    Making Connections Oakland: A Case Study for GCIR

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    GCIR profiles Making Connections Oakland (MCO), a comprehensive initiative that helps newcomers gain an economic foothold and become full participating members of society. The program was designed to build united neighborhoods and stronger families through strategies that illustrate the cornerstones of GCIR's Immigrant Integration Framework: mutual responsibility, change and benefits; multi-sector involvement; and multi-strategy approaches. Each method has its unique strengths with regard to immigrant integration and is highlighted in this document. As the examples in this report demonstrate, foundations do not need to build an immigrant integration program from scratch. Grantmakers can use resources that already exist in their communities to continue supporting their funding priorities

    Entanglement branes in a two-dimensional string theory

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    What is the meaning of entanglement in a theory of extended objects such as strings? To address this question we consider the spatial entanglement between two intervals in the Gross-Taylor model, the string theory dual to two-dimensional Yang-Mills theory at large NN. The string diagrams that contribute to the entanglement entropy describe open strings with endpoints anchored to the entangling surface, as first argued by Susskind. We develop a canonical theory of these open strings, and describe how closed strings are divided into open strings at the level of the Hilbert space. We derive the Modular hamiltonian for the Hartle-Hawking state and show that the corresponding reduced density matrix describes a thermal ensemble of open strings ending on an object at the entangling surface that we call an E-brane.Comment: 37 pages, 12 figures. v3: Modified title and abstrac

    Irreducible representations of the symmetric groups from slash homologies of p-complexes

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    In the 40s, Mayer introduced a construction of (simplicial) pp-complex by using the unsigned boundary map and taking coefficients of chains modulo pp. We look at such a pp-complex associated to an (n−1)(n-1)-simplex; in which case, this is also a pp-complex of representations of the symmetric group of rank nn - specifically, of permutation modules associated to two-row compositions. In this article, we calculate the so-called slash homology - a homology theory introduced by Khovanov and Qi - of such a pp-complex. We show that every non-trivial slash homology group appears as an irreducible representation associated to two-row partitions, and how this calculation leads to a basis of these irreducible representations given by the so-called pp-standard tableaux.Comment: 16 pages, 2 figures. Rewritten the proof of first theorem. Substantial rearrangement of materials in other sections. Comments welcome

    Regulation of tissue crosstalk by skeletal muscle-derived myonectin and other myokines.

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    The integrated control of animal physiology requires intimate tissue crosstalk, a vital task mediated by circulating humoral factors. As one type of these factors, adipose tissue-derived adipokines have recently garnered attention as important regulators of systemic insulin sensitivity and metabolic homeostasis. However, the realization that skeletal muscle also secretes a variety of biologically and metabolically active polypeptide factors (collectively called myokines) has provided a new conceptual framework to understand the critical role skeletal muscle plays in coordinating whole-body energy balance. Here, we highlight recent progress made in the myokine field and discuss possible roles of myonectin, which we have recently identified as a potential postprandial signal derived from skeletal muscle to integrate metabolic processes in other tissues, such as adipose and liver; one of its roles is to promote fatty acid uptake into cells. Myonectin is also likely an important mediator in inter-tissue crosstalk
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